Development of CRISPR-RNA Guided Recombinases for Genome Engineering
abstract: Recombinases are powerful tools for genome engineering and synthetic biology, however recombinases are limited by a lack of user-programmability and often require complex directed-evolution experiments to retarget specificity. Conversely, CRISPR systems have extreme versatility yet can ind...
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| Format: | Dissertation |
| Language: | English |
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2018
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| Online Access: | http://hdl.handle.net/2286/R.I.49261 |