INVESTIGATING MECHANISMS OF TRANSIENT RECEPTOR POTENTIAL REGULATION WITH NUCLEAR MAGNETIC RESONANCE AND ROSETTA COMPUTATIONAL BIOLOGY
abstract: The physiological phenomenon of sensing temperature is detected by transient receptor (TRP) ion channels, which are pore forming proteins that reside in the membrane bilayer. The cold and hot sensing TRP channels named TRPV1 and TRPM8 respectively, can be modulated by diverse stimuli an...
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| Format: | Doctoral Thesis |
| Language: | English |
| Published: |
2018
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| Online Access: | http://hdl.handle.net/2286/R.I.51630 |