The regulatory role of ROS on CXCR4 expression and function in prostate cancer cells

Inactivation of the tumor suppressor phosphatase and tensin liomolog deleted on chromosome 10 (PTEN) is heavily implicated in the tumorigenesis of prostate cancer. Conversely, the upregulation of the chemokine (CXC) receptor 4 (CXCR4) is associated with prostate cancer progression and metastasis. Th...

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Bibliographic Details
Main Author: Chetram, Mahandranauth A.
Format: Others
Published: DigitalCommons@Robert W. Woodruff Library, Atlanta University Center 2012
Subjects:
Online Access:http://digitalcommons.auctr.edu/dissertations/359
http://digitalcommons.auctr.edu/cgi/viewcontent.cgi?article=1887&context=dissertations