Ligand-macromolecule interactions

The optimisation of ligand-macromolecule interactions is fundamental to the design of therapeutic agents. The GRID method is a procedure for determining energetically favourable ligand binding sites on molecules of known structure using an empirical energy potential. In this thesis, it has been exte...

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Bibliographic Details
Main Author: Wade, R. C.
Other Authors: Goodford, Peter
Published: University of Oxford 1988
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236071