Analysis of gene expression in tumour immortalisation

Cellular senescence is an irreversible growth-arrested state seen in primary human cells after a finite number of cell divisions both in culture and <i>in vivo</i>. The escape from senescence to immortalisation is often thought to be a prerequisite for carcinogenesis. Many changes in sen...

Full description

Bibliographic Details
Main Author: Seow, Choon Sheong
Published: University of Aberdeen 2002
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251848