Synthesis and biochemical evaluation of inhibitors of estrone sulfatase as potential anti-tumour agents
In the treatment of hormone-dependent breast cancer, extensive research has been undertaken to produce compounds, which are both potent and selective inhibitors of the cytochrome P-450 enzyme aromatase. However, the use of aromatase inhibitors does not result in the inhibition of all of the biosynth...
| Main Author: | |
|---|---|
| Published: |
Kingston University
2003
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273709 |