Synthesis and biochemical evaluation of inhibitors of estrone sulfatase as potential anti-tumour agents
In the treatment of hormone-dependent breast cancer, extensive research has been undertaken to produce compounds, which are both potent and selective inhibitors of the cytochrome P-450 enzyme aromatase. However, the use of aromatase inhibitors does not result in the inhibition of all of the biosynth...
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Kingston University
2003
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273709 |