An investigation of enzyme mechanisms using substrate analogues
The synthesis of several fluorinated analogues of thiamine and precursors has been undertaken, all of which exhibit weak activity against E.Coli. A route to 3-fluoro-(R)-alanine has been explored. The first synthesis of the enantiomeric fluorosuccinic acids has been accomplished, and a stereochemica...
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University of Oxford
1980
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280143 |