Synthesis of novel amino acids as glutamate receptor antagonists and nitric oxide synthase inhibitors

A number of amino acids containing terminal five- and six-membered heterocyclic substituents have been synthesised using a strategy in which a 6-oxopipecolate system is 'ring switched'. Functionalisation of the protected (2S)-6-oxopipecolate at C-5 with methyl formate, or with allyl bromid...

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Bibliographic Details
Main Author: Philps, Oliver James
Published: University of Sussex 1999
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288834