Polymorphic variation and transcriptional regulation of muscarinic receptor genes in human airway cells

Muscarinic M2 and M3 receptors are important for the development of airway hyperresponsiveness in asthma. While there is currently no evidence to suggest altered function of M3 receptors in airway disease, a dysfunctionality of M2 receptors has been reported to occur in asthmatic patients. Current s...

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Bibliographic Details
Main Author: Fenech, Anthony
Published: University of Nottingham 2003
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289500