The application of fluorescence spectroscopy to the study of drug-protein binding

Many small molecules and drugs bind strongly to the plasma proteins and in particular to human serum albumin or HSA. The degree of binding of a drug to HSA may limit its availability to the receptor sites and excretory systems and so have profound effects on its biological activity and half-life. Va...

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Bibliographic Details
Main Author: Sturley, H. N.
Published: Loughborough University 1983
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.290344