Polyamine toxicity in mammalian cells in culture

The polyamines, spermidine and spermine, and their diamine precursor putrescine, act as both positive and negative regulators of cell growth. Their oxidation to growth inhibitory aminoaldehydes by a copper-dependent amine oxidase present in ruminant serum was initially thought to be responsible for...

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Bibliographic Details
Main Author: Brunton, Valerie G.
Published: University of Aberdeen 1990
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292363