Approaches to taxanes from carbohydrate precursors

This thesis is a continuation of the work by Bonnert to produce taxanes from glucose. The application of a Stork silyl methylene radical cyclisation to the allylic alcohol (1) led to the diol (2). This has a trans ring junction and has introduced regiospecifically a hydroxy methylene group adjacent...

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Bibliographic Details
Main Author: Howarth, Joshua
Published: University of Leicester 1990
Subjects:
547
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315226