Pterin biosynthesis, binding and modulation of eNOS catalytic function
Tetrahydrobiopterin (BH4) is a limiting cofactor for nitric oxide synthase (NOS) catalysed conversion of L-arginine to nitric oxide and citrulline. Content of BH4 in mammalian cells is regulated at many levels, but most important is de novo biosynthesis from GTP. GTP cyclohydrolase (GTPCH) is the ra...
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University of Surrey
2000
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326744 |