Investigation of the metabolism of N, N-Dimethylformamide and its metabolites
The industrial solvent N, N-dimethylformamide (DMF) causes liver damage in humans. The hepatotoxicity of N-alkylformamides seems to be linked to their metabolism to N-alkylcarbamic acid thioesters. To clarify the role of metabolism in DMF hepatotoxicity, the metabolic fate of DMF was investigated in...
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Aston University
1989
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.330157 |