The enzymatic and chemical synthesis of nucleoside analogues using N-deoxyribosyltransferase from Lactobacillus leichmannii

N-deoxyribosyltransferase catalyses the transfer of 2-deoxy-I 2.3, -dideoxyand 2,5-dideoxyribose sugars between purine and pyrimidine bases. In this work, a crude extract of N-deoxyribosyltransferase from Lactobacillus leichmannii was used in the chemoenzymatic synthesis of nucleoside analogues with...

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Bibliographic Details
Main Author: Hicks, Nicola
Published: University of Warwick 1992
Subjects:
579
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.332778