Use of cholera toxin to isolate mutants of Balb/c 3T3 mouse fibroblasts with defective ganglioside biosynthesis

Recent evidence has suggested that oncogenic transformation of mammalian tissue culture cells results in altered expression of several surface components. One of these changes is the reduced ability of transformed cells to synthesise complex gangliosides. This modification has been correlated with t...

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Bibliographic Details
Main Author: Streuli, Charles
Published: University of Leicester 1982
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.345627