Cytochrome P450 substrate specificities in rat, hamster and man

There are wide interspecies variations in the oxygenative cytochrome P450-dependent metabolism of foreign chemicals, and this has been shown to lead to species differences in chemical toxicity. This investigation studied a series of structurally similar substrates in rat, hamster and man. This appro...

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Bibliographic Details
Main Author: Thompson, Stephanie
Published: University of Aberdeen 1984
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.352063