The cyclisation of benzylaminoacetonitriles : evidence of exclusive participation of a spirocyclic intermediate

A survey has been made of isoquinoline preparation via Pomeranz-Fritsch and benzylaminoacetonitrile syntheses. Over the past fifteen years considerable effort has been made to establish the mechanism by which cyclisations of 3,4-dialkoxybenzylaminonitriles proceeds. Initially a dual mechanism was po...

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Bibliographic Details
Main Author: Hussain, Fazal
Published: University of Bath 1985
Subjects:
547
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.354728