The effect of folic acid and genetic polymorphisms on DNA stability and colorectal cancer

The aim of this study was to investigate the influence of folate on DNA stability and DNA methylation in three different systems. (i) Folate deficiency significantly increased DNA strand breakage and uracil misincorporation in human colon epithelial cells and lymphocytes in vitro. DNA methylation wa...

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Bibliographic Details
Main Author: Narayanan, Sabrina
Published: University of Aberdeen 2001
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369562