Cytochrome P-450-mediated ethoxy-resorufin Odeethylase activity measured in non-fixed, non-frozen sections using a fluorescence microscope

A highly sensitive method, based on the use of a microscope fluorimeter and fluorogenic substrates, is being developed to measure rates of drug-metabolising enzyme reactions in small areas of cells in thin liver sections. The results described here illustrate a method in which reaction rates were me...

Full description

Bibliographic Details
Main Author: Sullivan, Maureen
Published: University of Aberdeen 1985
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370113