Study of the role of an oncogene in the formation of tumours

The aim of this study was to examine the claim that a single, mutant oncogene can transform NIH 3T3 mouse fibroblasts into transformed, tumorigenic cells, acting in a genetically dominant fashion. A c.Ha-ras 1 oncogene, cloned from the EJ human bladder carcinoma cell line, was inserted into a shuttl...

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Bibliographic Details
Main Author: Gilbert, P. X.
Other Authors: Harris, Henry
Published: University of Oxford 1986
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376922