Post-translational processing of proteins implicated in the pathogenesis of Alzheimer's disease
The beta-amyloid peptide characteristic of the lesions of Alzheimer's disease (AD) is derived from the amyloid precursor protein (APP), a single transmembrane-spanning protein with several alternatively-spliced variants, some of which contain a Kunitz protease inhibitory (KPI) domain. Although...
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Sheffield Hallam University
2001
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392274 |