Role of Base and nucleotide excision repair pathways in processing of clustered DNA lesions induced by ionising radiation

Ionising radiation (IR) induces a wide spectrum of lesions in DNA, including double- and single-strand breaks, abasic (AP) sites and a variety of base lesions. IR-induced damage to DNA can range from simple, isolated lesions to clustered DNA damage in which multiple lesions are formed, usually withi...

Full description

Bibliographic Details
Main Author: Budworth, Helen Louise
Published: University of Oxford 2003
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398139