Differential expression of connective tissue growth factor (CTGF) in fibrogenesis : regulation by simvastatin
Connective Tissue Growth Factor (CTGF) is a potent, pro fibrotic mediator, which acts downstream of and in concert with Transforming Growth Factor (TGF)p, to drive fibrogenesis. Significant upregulation of CTGF has been reported in fibrogenic diseases including idiopathic pulmonary fibrosis (IPF). I...
| Main Author: | |
|---|---|
| Published: |
Keele University
2004
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398915 |