Cisplatin nephrotoxicity in vivo and in vitro and the use of the immediate early genes c-Fos and c-Jun as early markers of toxicity
The aim of this thesis is to investigate the mechanism of cisplatin nephrotoxicity and to examine the responses of rat and human proximal tubular cell cultures to platinum analogues for potential early markers of toxicity. Nephrotoxicity was induced in male Sprague Dawley rats (N = 4 +/- standard de...
| Main Author: | |
|---|---|
| Published: |
University of Aberdeen
2004
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401163 |