Mechanistic probes to the enediyne anticancer antibiotics
The work described in this thesis details the design, synthesis and evaluation of molecules intended as mechanistic probes to the enediyne anticancer antibiotics. In particular it examines the role of radical and ionic accepting groups in analogue systems related to the DNA cleaving agent Neocarzino...
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University of Sussex
1999
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401478 |