Anti-tumour properties of novel diaziridinylquinones

This work is concerned with the synthesis and potential anti-tumour properties of novel Diaziridinylquinones. These types of compounds are usually activated by bioreduction to form cytotoxic species, which alkylate DNA and block cells in the G 2 /M phase of the cell cycle. However, the present studi...

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Bibliographic Details
Main Author: Di Francesco, Angela Maria
Published: University of Salford 2001
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402645