The shikimate pathway : enzymes and antimicrobials
(6S)-6-Fluoroshikimic acid 1 was developed as a potential antimicrobial which was converted to 6-fluorochorismate 2 and hence targeted the post-chorismate pathway to p-aminobenzoic acid 2 and folic acid (fig. 1). Although successful against microbial challenge, resistance developed rapidly. This res...
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University of Glasgow
2004
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.411846 |