Molecular and biochemical characterisation of key enzymes involved in mycolic acid biosynthesis from Mycobacterium tuberculosis

Mycolic acids are the dominant feature of the Mycobacterium tuberculosis cell wall, providing the basis for its lipid-rich permeability barrier. These oc-alkyl, P-hydroxy fatty acids are thought to be formed by the Claisen-typec ondensationo f a long C56m eromycolic acid and a shorter C24-C2f6a tty...

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Bibliographic Details
Main Author: Brown, Alistair Karl
Published: University of Newcastle Upon Tyne 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413941