Expansion of the replicative lifespan of human muscle cells by retroviral transduction of the catalytic telomerase subunit gene

Duchenne Muscular Dystrophy (DMD) is a genetic disorder which is caused by mutations in the dystrophin gene.  One of the functions of this protein is to anchor the cell membrane to the sacrolemma.  In DMD, the absence of this protein leads to muscle damage during contractions, resulting in continuou...

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Bibliographic Details
Main Author: Wootton, Martha
Published: University of Glasgow 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414119