The roles of annexins 1 and 2 in receptor-mediated endocytosis
Activated EGF receptors (EGFR) are sorted onto internal vesicles of multivesicular endosomes/bodies (MVBs), thus removing receptors from the recycling pathway and targeting them for degradation. The EGFR tyrosine kinase has two major substrates within MVBs, the EGFR itself and annexin 1. Annexins ha...
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University College London (University of London)
2005
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414712 |