The Saccharomyces cerevisiae SNM1 gene and repair of anticancer drug-induced DNA interstrand cross-links
Saccharomyces cerevisiae (budding yeast) cells defective for the PSO2/SNM1 gene are uniquely sensitive to agents that produce DNA interstrand cross-links (ICLs), but not other forms of DNA damage. In the absence of Pso2, repair is stalled after the initial incision of ICLs, resulting in an accumulat...
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University College London (University of London)
2004
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415564 |