Characterisation of alloreactive helper T-cell epitopes on the platelet membrane GPIIIa (integrin β3)

The HPA-1a antigen is the most immunogenic and clinically important antigen of the human platelet antigen (HPA) system.  It is a major target in neonatal alloimmune thrombocytopenic purpura (NAITP).  As a first step towards peptide immunotherapy for NAITP, the aim was to map immunodominant helper ep...

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Bibliographic Details
Main Author: Sukati, Hosea M.
Published: University of Aberdeen 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420123