Directed evolution of transketolase, a carbon-carbon bond-forming enzyme

The enzyme transketolase (Enzyme Commission number: 2.2.1.1) has significant potential as a biocatalyst in the production of pharmaceuticals and fine chemicals. The enzyme catalyses the irreversible transfer of a C2 (1,2-dihydroxyethyl) moiety from p-hydroxypyruvate (P-HPA) to a wide range of accept...

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Bibliographic Details
Main Author: Miller, Oliver J.
Published: University College London (University of London) 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420615