Evidence for a novel tumour suppressor gene at 10q21 chromosome in sporadic colorectal adenocarcinoma

This thesis sought to define deletions of chromosome lOin sporadic colorectal adenocarcinoma and determine their role in colorectal tumorigenesis. This thesis has shown a region of frequent loss of heterozygosity (LOH) in the region lOql1-21 centring on the marker D10S1790 at lOq21 suggesting this i...

Full description

Bibliographic Details
Main Author: Fawole, Adeshina Sergei
Published: Keele University 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.421667