Synaptotagmin IV function in secretory granule maturation in neuroendocrine cells

In neuroendocrine cells, immature secretory granules (ISGs) bud from the trans Golgi network (TGN), and then undergo a maturation process that includes ISG-ISG homotypic fusion, removal of excess membranes via clathrin-coated vesicles (CCVs) and acidification of the granules. These mature secretory...

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Bibliographic Details
Main Author: Ahras, Malika
Published: University College London (University of London) 2005
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Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425667