The role and regulation of elF2α phosphorylation in pancreatic β-cells

Incubation of pancreatic beta-cells or islets with glucose leads to acute increases in the rate of total protein synthesis, which are almost entirely regulated at the post-transcriptional level. However, the metabolic signals and the molecular mechanisms by which glucose stimulates increases in the...

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Bibliographic Details
Main Author: Powell, Michael L.
Published: University of Leicester 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430243