Genetic susceptibility to radiation-induced acute myeloid leukaemia (r-AML)

CBA/H inbred mice are susceptible to radiation-induced acute myeloid leukaemia (r-AML) while C57BL/6 mice are resistant to r-AML. CBA/H mice also have higher haemopoietic stem cell number (HSC) than C57BL/6 mice raising the possibility that HSC frequency is a risk factor in r-AML. F2 mice were there...

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Bibliographic Details
Main Author: Jawad, Mays Safa Hadi
Published: University of Leicester 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431421