Characterisation of the Raf protein kinases by gene targeting

The role of B-Raf in cell growth and survival was investigated using primary MEFs lacking B-Raf. Cell growth and proliferation were found to be reduced and this coincided with alterations in the expression levels of various proteins involved in the G1 to S phase of the cell cycle. Analysis of B-raf...

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Bibliographic Details
Main Author: Hussain, Jahan Nurany
Published: University of Leicester 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431981