The role and regulation of caspases during T cell activation and proliferation
In the present study, the effects of two caspase inhibitors, z-VAD-FMK and z-IETD-FMK, on T cell activation and proliferation were compared to the negative control, z-FA-FMK. All three compounds inhibited T cell proliferation, blast formation, CD25 expression, IL-2 signalling and nuclear translocati...
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University of Leicester
2006
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432989 |