Studies on the specificities of in vivo and in vitro bioassays used in the potency determination of therapeutic erythropoietin
Erythropoietin (Epo), a kidney-produced cytokine, promotes the proliferation and differentiation of erythroid progenitors into mature red blood cells. The <i>in vivo</i> biological activity of Epo is dependent on it being adequately glycosylated. Glycosylation is a variable process and i...
| Main Author: | |
|---|---|
| Published: |
Open University
2006
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437320 |