Post-translational modification and sequestration of cAMP-specific phosphodiesterase 4 in signalling complexes
cAMP is a ubiquitous second messenger that is pivotal in controlling a wide array of cellular functions. The sole means to inactivate cAMP is to degrade it into 5'- AMP through the action of cyclic nucleotide phosphodiesterases (PDEs). It is now well appreciated that cAMP hydrolysis by PDEs is...
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University of Glasgow
2006
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Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.443392 |