Post-translational modification and sequestration of cAMP-specific phosphodiesterase 4 in signalling complexes

cAMP is a ubiquitous second messenger that is pivotal in controlling a wide array of cellular functions. The sole means to inactivate cAMP is to degrade it into 5'- AMP through the action of cyclic nucleotide phosphodiesterases (PDEs). It is now well appreciated that cAMP hydrolysis by PDEs is...

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Bibliographic Details
Main Author: Li, Xiang
Published: University of Glasgow 2006
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.443392