Interactions of some methylenedioxyphenyl compounds with hepatic microsomal cytochromes P-450

This study has investigated the interactions of a number of methyl-enedioxyphenyl compounds with hepatic cytochrome P-450. The administration of isosafrole to rats resuited in the formation of an in vivo isosafrole metabolite-cytochrome P-450 complex which caused inhibition of the hepatic monooxygen...

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Bibliographic Details
Main Author: Sweatman, Brian Charles
Published: University of Surrey 1979
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.474335