NMR structure of the S-domain of calreticulin, the sub-fragment that comprises the calreticulin binding site for defence collagens
Using the overlapping sub-fragments, i.e. P-, S- and SP-domains of CRT in different binding assays, we determined that the S-domain has the strongest affinity to bind to C1q and MBL. This makes the structure of the S-domain most relevant for understanding the binding interactions to C1q and MBL and...
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University of Leicester
2004
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.483577 |