Investigating DNA Double Strand Breaks (DSB) in mammalian cells by novel fluorescent reporters

An efficient DNA damage response is critical for maintaining the integrity of the mammalian genome, and ensuring the accurate transfer of genetic information between generations. Of particular biological relevance are DNA double strand breaks (DSB), which if repaired incorrectly may contribute to ca...

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Bibliographic Details
Main Author: Riches, Lucy C.
Other Authors: Gooderham, Nigel ; Lynch, Anthony
Published: Imperial College London 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.484730