Investigating the function of the retention/retrieval, ERp57-binding and glycan-binding sites of calreticulin in MHC class I antigen presentation
Calreticulin (CRT) is an Endoplasmic Reticulum (ER) resident protein involved in intracellular calcium homeostasis and the folding of newly synthesised glycoproteins. CRT also forms part of the peptide loading complex (PLC) where it assists in Major Histocompatibility Complex (MHC) class I folding,...
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University of Southampton
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485036 |