cAMP-Mediated Responses in Human Airway Smooth Muscle Cells and Epithelial Cells: Roles for PKA?
p2-Adrenoceptor agonists are a mainstay in asthma therapy and act via adenylyl cyclase to increase intraceJlular cyclic adenosine-3 ,5 -monophosphate (cAMP). Upon binding ofcAMP to the regulatory subunits of protein kinase A (PKA), there is dissociation of the catalytic subunits. These may then phos...
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Imperial College London
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485409 |