Inhibition of Arp2/3-mediated actin polymerisation by PICK1 drives AMPA receptor endocytosis
Increasing evidence suggests that the dynamic regulation of the actin cytoskeleton is the principal driving factor for endocytosis, however, the mechanistic details and proteins involved remain unclear. PICK1 is a modular PDEZ-BAR domain protein that can bind the AMPA receptor (AMPAR) subunits GluR2...
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University of Bristol
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486081 |