Molecular cloning and characterization of osteopontin target genes in rat mammary epithelial cells

Osteopontin (OPN) is a secreted, integrin binding and phosphorylated acidic glycoprotein which has an important role in tumor development including adhesion, invasion and metastasis. High OPN expression in the primary tumour is associated with early metastasis and poor outcome, in human beast and ot...

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Bibliographic Details
Main Author: Kurisetty, Vittal Venkatasatya
Published: Queen's University Belfast 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486232